I’ve seen people talk about actors and artists that had a terrible time.
My own would be Anne Rice. She wrote Interview with the Vampire after her young daughter died of Leukemia. Then her husband suddenly died of a brain hemorrhage. I suspect her Christian, anti-fanfic phase was a result of mental illness and manipulation from the publishers, although I don’t think she ever apologized.
Hemmingway, his battle with mental illness, addiction, physical injury ultimately ended in his suicide and is a tragic story all on its own.
He was a mans man who died as no man should.