Why do you have 17 mini pc? What are you doing with them?

I agree with one of the users. It’s going to use. A bunch of power and its going to be a space heater. You should just get a regular computer. This is a very odd ball thing. But yes it will be able to run plex. But also you can run plex on a ras pi but have it okay via direct play. I don’t use pi. I have. Amd ryzen 7 3700x with 64 gb of ram for my plex served.