All real life laws and logic apply.

You have 24 hours to modify your car before departure, so mods must be reasonable within the time frame, no v10 swapped awd civics for example, logistically impossible in 24 hours.

Police activity matters, but you’re working for the feds so the local police won’t cross state lines, leaving a jurisdiction could get them off you, states with no pursuit laws can work in your favor, etc.

Refueling is required, gas mileage matters, EV might be risky with charge times. Running E85 might be to sparse to run.

You can deviate from i90, but it’s the fastest route so riding purely backroads probably won’t suffice

2 goon cars will pursue you every 8 hours. They drive new base Mercedes G wagons and C class’s

You can have as many companions as your car has seats, feel free to take a 4 seat sedan with 3 pals ready to blast some goons if you have to.

You depart tomorrow, so weather is a factor, expect freezing temperatures at some points in certain states. You’ll see rain, dry pavement, maybe icy roads or snow.

Personally I’d likely choose some sort of low key, moderately fuel efficient sedan/suv/wagon with AWD, and enough pep to not get easily chased down on the highway. Maybe a generic tuned BMW 330xi with variable boost. If I follow my heart though, I’m taking a new M5 comp